In the problems of image retrieval and few-shot classification, the mainstream approaches focus on learning a better feature representation.

Longitudinal imaging analysis tracks disease progression and treatment response over time, providing dynamic insights into treatment efficacy and disease evolution. Radiomic features extracted from medical imaging can support the study of disease progression and facilitate longitudinal prediction of clinical outcomes. This study presents a probabilistic model for longitudinal response prediction, integrating baseline features with intermediate follow-ups. The probabilistic nature of the model naturally allows to handle the instrinsic uncertainty of the longitudinal prediction of disease progression. We evaluate the proposed model against state-of-the-art disease progression models in both a synthetic scenario and using a brain cancer dataset. Results demonstrate that the approach is competitive against existing methods while uniquely accounting for uncertainty and controlling the growth of problem dimensionality, eliminating the need for data from intermediate follow-ups.

CTBench is introduced as a benchmark to assess language models (LMs) in aiding clinical study design. Given study-specific metadata, CTBench evaluates AI models' ability to determine the baseline features of a clinical trial (CT), which include demographic and relevant features collected at the trial's start from all participants. These baseline features, typically presented in CT publications (often as Table 1), are crucial for characterizing study cohorts and validating results. Baseline features, including confounders and covariates, are also necessary for accurate treatment effect estimation in studies involving observational data. CTBench consists of two datasets: "CT-Repo," containing baseline features from 1,690 clinical trials sourced from clinicaltrials.gov, and "CT-Pub," a subset of 100 trials with more comprehensive baseline features gathered from relevant publications. Two LM-based evaluation methods are developed to compare the actual baseline feature lists against LM-generated responses. "ListMatch-LM" and "ListMatch-BERT" use GPT-4o and BERT scores (at various thresholds), respectively, for evaluation. To establish baseline results, advanced prompt engineering techniques using LLaMa3-70B-Instruct and GPT-4o in zero-shot and three-shot learning settings are applied to generate potential baseline features. The performance of GPT-4o as an evaluator is validated through human-in-the-loop evaluations on the CT-Pub dataset, where clinical experts confirm matches between actual and LM-generated features. The results highlight a promising direction with significant potential for improvement, positioning CTBench as a useful tool for advancing research on AI in CT design and potentially enhancing the efficacy and robustness of CTs.

The advancement of deep learning technologies is bringing new models every day, motivating the study of scalable model selection. An ideal model selection scheme should minimally support two operations efficiently over a large pool of candidate models: update, which involves either adding a new candidate model or removing an existing candidate model, and selection, which involves locating highly performing models for a given task. However, previous solutions to model selection require high computational complexity for at least one of these two operations. In this work, we target fundamentally (more) scalable model selection that supports asymptotically fast update and asymptotically fast selection at the same time. Firstly, we define isolated model embedding, a family of model selection schemes supporting asymptotically fast update and selection: With respect to the number of candidate models $m$, the update complexity is O(1) and the selection consists of a single sweep over $m$ vectors in addition to O(1) model operations. Isolated model embedding also implies several desirable properties for applications. Secondly, we present Standardized Embedder, an empirical realization of isolated model embedding. We assess its effectiveness by using it to select representations from a pool of 100 pre-trained vision models for classification tasks and measuring the performance gaps between the selected models and the best candidates with a linear probing protocol. Experiments suggest our realization is effective in selecting models with competitive performances and highlight isolated model embedding as a promising direction towards model selection that is fundamentally (more) scalable.

Online transaction fraud presents substantial challenges to businesses and consumers, risking significant financial losses. Conventional rule-based systems struggle to keep pace with evolving fraud tactics, leading to high false positive rates and missed detections. Machine learning techniques offer a promising solution by leveraging historical data to identify fraudulent patterns. This article explores using the personalised PageRank (PPR) algorithm to capture the social dynamics of fraud by analysing relationships between financial accounts. The primary objective is to compare the performance of traditional features with the addition of PPR in fraud detection models. Results indicate that integrating PPR enhances the model's predictive power, surpassing the baseline model. Additionally, the PPR feature provides unique and valuable information, evidenced by its high feature importance score. Feature stability analysis confirms consistent feature distributions across training and test datasets.

Automatic detection and severity level classification of dysarthria directly from acoustic speech signals can be used as a tool in medical diagnosis. In this work, the pre-trained wav2vec 2.0 model is studied as a feature extractor to build detection and severity level classification systems for dysarthric speech. The experiments were carried out with the popularly used UA-speech database. In the detection experiments, the results revealed that the best performance was obtained using the embeddings from the first layer of the wav2vec model that yielded an absolute improvement of 1.23% in accuracy compared to the best performing baseline feature (spectrogram). In the studied severity level classification task, the results revealed that the embeddings from the final layer gave an absolute improvement of 10.62% in accuracy compared to the best baseline features (mel-frequency cepstral coefficients).

Characterizing meltpool shape and geometry is essential in metal Additive Manufacturing (MAM) to control the printing process and avoid defects. Predicting meltpool flaws based on process parameters and powder material is difficult due to the complex nature of MAM process. Machine learning (ML) techniques can be useful in connecting process parameters to the type of flaws in the meltpool. In this work, we introduced a comprehensive framework for benchmarking ML for melt pool characterization. An extensive experimental dataset has been collected from more than 80 MAM articles containing MAM processing conditions, materials, meltpool dimensions, meltpool modes and flaw types. We introduced physics-aware MAM featurization, versatile ML models, and evaluation metrics to create a comprehensive learning framework for meltpool defect and geometry prediction. This benchmark can serve as a basis for melt pool control and process optimization. In addition, data-driven explicit models have been identified to estimate meltpool geometry from process parameters and material properties which outperform Rosenthal estimation for meltpool geometry while maintaining interpretability.

Unsupervised learning seeks to uncover patterns in data. However, different kinds of noise may impede the discovery of useful substructure from real-world time-series data. In this work, we focus on mitigating the interference of left-censorship in the task of clustering. We provide conditions under which clusters and left-censorship may be identified; motivated by this result, we develop a deep generative, continuous-time model of time-series data that clusters while correcting for censorship time. We demonstrate accurate, stable, and interpretable results on synthetic data that outperform several benchmarks. To showcase the utility of our framework on real-world problems, we study how left-censorship can adversely affect the task of disease phenotyping, resulting in the often incorrect assumption that longitudinal patient data are aligned by disease stage. In reality, patients at the time of diagnosis are at different stages of the disease -- both late and early due to differences in when patients seek medical care and such discrepancy can confound unsupervised learning algorithms. On two clinical datasets, our model corrects for this form of censorship and recovers known clinical subtypes.

A few examples with custom CNN design include acoustic in several machine learning tasks such as image classification, modeling for low resource languages [8], object and action classification object tracking, and keyword spotting. However, given that [9] and remote sensing [10]. On the other hand, medical image they contain a large number of parameters, their direct applicability classification [11] requires assignment of medical images (drawn into low resource tasks is not straightforward. In this work, we from real world patients) to a medical landmark, phenomenon or a experiment with an application of CNN models to gastrointestinal disease and often, obtaining large amounts of training data can be landmark classification with only a few thousands of training samples challenging. A few approaches for medical image classification include through transfer learning. As in a standard transfer learning the use of decision trees [12], k-nearest-neighbors [13] and approach, we train CNNs on a large external corpus, followed by support vector machines [14].